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Group B Streptococcus

The UK NSC policy on Group B Streptococcus screening in pregnancy

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GBS is one of many bacteria that can be present in our bodies. It usually causes no harm. This situation is called carrying GBS or being colonised with GBS. GBS is commonly found in the digestive system and the female reproductive system. It's estimated that about one in four pregnant women in the UK carry GBS.

Around the time of labour and birth, many babies come into contact with GBS and are colonised by the bacteria. Most pregnant women who carry GBS bacteria have healthy babies. However, there's a small risk that GBS can pass to the baby during childbirth. Rarely, GBS infection in newborn babies can cause serious complications that can be life-threatening.

Extremely rarely, GBS infection during pregnancy can also cause miscarriage, early (premature) labour or stillbirth. If a baby develops GBS infection less than seven days after birth, it's known as early-onset GBS infection. Most babies who become infected develop symptoms within 12 hours of birth.

It's estimated that about one in 2,000 babies born in the UK and Ireland develops early-onset GBS infection. This means that every year in the UK (with 680,000 births a year) around 340 babies will develop early-onset GBS infection.

There are a number of clinical risk factors which increase the risk of EOGBS sepsis. These include preterm birth (less than 37 weeks gestation), prolonged rupture of the membranes and maternal fever in labour. In the UK healthcare professionals are encouraged to identify and manage high risk pregnancies on the basis of an assessment of these risk factors.

The Royal College of Obstetricians and Gynaecologists have published a guideline for professionals and information for the public.

» View the professional guideline

» View the public information

Policy Position

Screening for this condition should not be offered.

This policy was reviewed in Nov 2008 but no significant changes were made. It is due to be considered again in 2011/12, or earlier if significant new evidence emerges.

Evidence Supporting the Policy

See the review against UK NSC criteria, below.

Presentations from the stakeholder meeting in November 2008, are also available.

Stakeholders

Group B Strep Support
Health Protection Agency
Royal College of Obstetricians and Gynaecologists

The stakeholder groups will be involved when the policy is next reviewed. If you think your organisation should be added, please contact us.

Related documents

Review of antenatal screening for Group B Streptococcus (October 2008) (PDF document, 93KB, 05/10/09)

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